Pyrimethamine, Artesunate & Sulfadoxine Tablets
Price And Quantity
- 1.50-2.00 USD ($)
- General Medicines
- Pyrimethamine, Artesunate And Sulfadoxine Tablets 100mg + 500mg + 25mg
- AS DIRECTED BY PHYSICIAN
- As Per Directed By Physician
- Suitable For All
- 10000 Unit
- Store at Dry and Cool Place.
- Artesunate, Sulphadoxine and Pyrimethamine Tablet is the mixture is given to be effective in treating malaria caused by Plasmodium falciparum than that caused by P.
- vivax, that chloroquine is given effective, though within the absence of a species-specific diagnosis, the sulfadoxine-pyrimethamine and therefore the combination could also be indicated the first-line treatment for children or adults with severe malaria, usually together with another antimalarial.
- Artesunate is a prodrug thass rapidly converted to its active form dihydroartemisinin (DHA). This process involves the hydrolysis of the 4-carbon ester group via plasma esterase enzyme.
- ItÃÂ¢ÃÂÃÂs hypothesized that the cleavage of the endoperoxide bridge within the pharmacophore of DHA generates reactive oxygen species (ROS), which increases oxidative stress and causes malarial protein damage via alkylation.
- Sulfadoxine is a sulfonamide antibiotic that competes with p-aminobenzoic acid within the biosynthesis of folate. Pyrimethamine is a selective inhibitor of protozoal dihydrofolate reductase, hence preventing the synthesis of tetrahydrofolate the active sort of folate.
- Hypersensitivity reactions (e.g. itchiness, dermatitis, and hives)
- Gastrointestinal effects (e.g. nausea, vomiting, and diarrhoea)
- Nhavasheva Port, Mundra Port, Hajira Port.
- Western Union, Telegraphic Transfer (T/T), Letter of Credit (L/C), Cash in Advance (CID), Cash Advance (CA)
- 10000 Per Day
- 5-7 Days
- If order is confirmed we will reimburse the sample cost
- Alualu, Blister
- Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
- All India
C-75, Sumeru City Mall, Sudama Chowk, opp. Krishna Township, Mota Varachha,, Surat, Gujarat, 394101, India